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Adverse Drug Event Causality Analysis (ADECA): a process for evaluating evidence and assigning drugs to risk categories for sudden death - Woosley RL, Romero K, Heise CW, Gallo T, Tate J, Woosley RD, Ward S.

Growing evidence indicates that many drugs have the ability to cause a potentially lethal cardiac arrhythmia, torsades de pointes (TdP). This necessitates the development of a compilation of drugs that have this potential toxicity. Such a list is helpful i...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

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Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Correspondence Source Type: research
ConclusionsThere was a high prevalence of vitamin D deficiency in the elderly, and the evidence shows a strong association between vitamin D deficiency and increased risk of heart failure in this population.
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
Authors: Chu T, Azevedo K, Ernst AA, Sarangarm D, Weiss SJ Abstract OBJECTIVES: Patients with an alcohol use disorder experiencing acute intoxication or withdrawal may be at risk for electrocardiograph (ECG) abnormalities, including prolongation of repolarization (long QTc [corrected QT]) that may contribute to arrhythmias and may be associated with a threefold increase in the likelihood of sudden cardiac events. Patients with acute coronary syndrome may have prolonged QTc as well. To our knowledge, no previous studies have compared the QTc of ACS with acute ethanol (EtOH) withdrawal syndromes in the emergency depa...
Source: Southern Medical Journal - Category: General Medicine Tags: South Med J Source Type: research
Abstract Atrial fibrillation (AF) is a common cardiac arrhythmia, and pathological burden can be influenced by environmental factors. The rural environment may influence the burden of AF, although no systematic review studies have been conducted to address this issue. We performed a systematic review of AF screening studies conducted in rural global populations to determine the burden, risk factors, and screening methods surrounding AF in these settings. Out of the 1792 articles gathered from a keyword search of medical databases and reference lists, 18 publications from 11 countries were included in our analysis....
Source: Baylor University Medical Center Proceedings - Category: Universities & Medical Training Authors: Tags: Proc (Bayl Univ Med Cent) Source Type: research
This editorial refers to ‘Alcohol consumption, sinus tachycardia, and cardiac arrhythmias at the Munich Octoberfest: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW)’††, by S. Brunneret al., on page2100.
Source: European Heart Journal - Category: Cardiology Source Type: research
INTRODUCTION: Alcohol intoxication in infants is a life-threatening condition which requires early diagnosis and treatment. It may lead to multi-system injury, including mental deterioration, respiratory depression, cardiac arrhythmia, metabolic disorders ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news
Conclusion This cross-sectional study found binge drinking is associated with an increased risk of having an irregular heartbeat. However, the type of irregular heartbeat found was mainly sinus tachycardia, which isn't life threatening but involves the heart beating at an abnormally fast rate of over 100 heartbeats a minute. This research also has some notable limitations: The ECG recordings from the acute alcohol group were taken using a smartphone application operated outside the manufacturer's recommended environment. The lively atmosphere within the beer tent may have caused inaccurate recordings. The population...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Lifestyle/exercise Source Type: news
AbstractAimsAlcohol is a risk factor for cardiac arrhythmias. Retrospective analyses suggest supraventricular arrhythmias consecutive to acute alcohol consumption, but prospective data are limited. We intended to prospectively associate acute alcohol consumption with cardiac arrhythmias.Methods and resultsAt the 2015 Munich Octoberfest, we enrolled 3028 voluntary participants who received a smartphone-based ECG and breath alcohol concentration (BAC) measurements. ECGs were analysed for cardiac arrhythmias (sinus tachycardia, sinus arrhythmia, premature atrial/ventricular complexes, atrial fibrillation/flutter) and respirat...
Source: European Heart Journal - Category: Cardiology Source Type: research
Conclusions: Short-term wearing of particulate-filtering respirators may produce cardiovascular benefits by improving autonomic nervous function and reducing BP. Citation: Shi J, Lin Z, Chen R, Wang C, Yang C, Cai J, Lin J, Xu X, Ross JA, Zhao Z, Kan H. 2017. Cardiovascular benefits of wearing particulate-filtering respirators: a randomized crossover trial. Environ Health Perspect 125:175–180; http://dx.doi.org/10.1289/EHP73 Address correspondence to H. Kan, Department of Environmental Health, School of Public Health, Fudan University, P.O. Box 249, 130 Dong-An Rd., Shanghai 200032, China. Telephone: 86 (21) 5423 7...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Articles February 2017 Source Type: research
Hypothermia is a life threatening condition that may result in death. It is a drop in the core body temperature of less than 95°F (35° Celsius). This temperature is below what is required for normal metabolism and bodily function (Figure 1). The normal body temperature is between 97.7°F and 99.5°F (Fahrenheit) which is the same as 36.5°C and 37.5°C (Celsius). The body's thermoregulation mechanism adjusts to weather changes. Thermoregulation During extreme cold, the body receives a signal from sensory receptors. The signal will go up to the brain. The brain then sends a signal to the body to resp...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
More News: Alcoholism | Arrhythmia | Cardiac Arrhythmia | Toxicology