Effect of Munghurt Lactobacillus acidophilus from Green Beans to Blood Glucose Levels in Alloxan-induced Diabetic Rats
The objective of this research was to determine effect of munghurt Lactobacillus acidophilus to blood glucose levels in diabetic rats induced alloxan. Materials and Methods: The samples (n=25) were divided into five groups, negative control (Negative); positive control (Positive); glibenclamide-treated (Glibenclamide); munghurt Lactobacillus acidophilus-treated (Munghurt); glibenclamide and munghurt Lactobacillus acidophilus combination-treated (Glibenclamide+Munghurt). Diabetes rat was induced by an intraperitoneal injection of alloxan. Munghurt Lactobacillus acidophilus was orally administered to normal and diabetic rats for a period of 4 weeks. Blood glucose level was observed on 0 and 28 days. Data were statistically analyzed using Kruskall Wallis and Mann Whitney test and further by one way ANOVA and Tukey post hoc test. Results: Munghurt Lactobacillus acidophilus decreased blood glucose level significantly on 28 days (p = 0.001) with blood glucose level mean of 87.32±5.15 mg dL1 (negative), 233±17.323 mg dL1 (positive), 117.36±8.153 mg dL1 (munghurt), 105.46±3,756 mg dL1 (glibenclamide) and 105±4.617 mg dL1 (munghurt+glibenclamide) respectively. Munghurt Lactobacillus acidophilus combined with glibenclamide had best results at lowering blood glucose in diabetic rats (p
TYPE 2 DIABETES symptoms include passing more urine than usual and feeling tired all the time. If the condition is left untreated, a number of other health problems can follow, so it ’s important to recognise all the signs - including feeling very thirsty.
This NIHR Signal finds that for western high-income countries such as the UK, an estimated 15% to 16% of cancers could be avoided by preventing diabetes, obesity or excess weight. Although the links between high BMI, diabetes and cancer have been known for some time, this study presents the first calculations of attributable risk for 175 countries. This represents the proportion of cancers that could be prevented if the risk factors were eliminated.
Diabetic patients are more prone to the development of foot ulcers, because their underlying tissues are exposed to colonization by various pathogenic organisms. Hence, biofilm formation plays a vital role in disease progression by antibiotic resistance to the pathogen found in foot infections. The present study has demonstrated the correlation of biofilm assay with the clinical characteristics of diabetic foot infection. The clinical characteristics such as the ulcer duration, size, nature, and grade were associated with biofilm production.
This article is protected by copyright. All rights reserved.
Yi-Guang Chen, Clayton E. Mathews, John P. Driver
This article provides insight into the clinical manifestations of CDC73-related disorders and discusses ways to improve case detection in primary hyperparathyroidism.Journal of Clinical Endocrinology &Metabolism
Find out how muscle function and exercise performance are impacted among patients receiving statin treatment.Journal of Clinical Endocrinology &Metabolism
New J. Chem., 2018, Advance Article DOI: 10.1039/C7NJ04678B, PaperS. Ferreira, A. Leite, T. Moniz, M. Andrade, L. Amaral, B. de Castro, M. Rangel EPR/51V-NMR parallel studies of [VO(3,4-HPO)2] complexes in MOPS buffer and POPC liposome suspensions provide information regarding solvents for oral administration. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Authors: Zhang X, Chee WK, Liu S, Tavintharan S, Sum CF, Lim SC, Kumari N Abstract Purpose: Osteopontin (OPN) is a proinflammatory cytokine with diverse functions. Increased levels of OPN in vitreous fluid have been reported in patients with diabetic retinopathy (DR); however, studies on circulating OPN levels in DR are limited. We aim to examine the association of plasma OPN levels with the presence and severity of DR in a multiethnic cohort with type 2 diabetes mellitus (type 2 diabetes) in Singapore. Methods: Plasma levels of OPN were measured using enzyme-linked immunosorbent assay. Digital color fundus pho...
This article summarizes the milestones in the development of ertugliflozin leading to its first approval for T2DM.