Expression of Trans- and Paracellular Calcium and Magnesium Transport Proteins in Renal and Intestinal Epithelia During Lactation.

In conclusion, proteins involved in transcellular Ca2+ and Mg2+ transport pathways increase during lactation, while expression of paracellular transport proteins remained unchanged. Increased fractional Ca2+ excretion can be explained by vitamin D-dependent intestinal hyperabsorption and bone demineralization, despite enhanced transcellular Ca2+ uptake by the kidney.
PMID: 28539338 [PubMed - as supplied by publisher]

Source: Am J Physiol Renal P... - May 24, 2017 Category: Urology & Nephrology Authors: Beggs MR, Appel I, Svenningsen P, Skjødt K, Alexander RT, Dimke H Tags: Am J Physiol Renal Physiol Source Type: research