A case of congenital Langerhans cell histiocytosis with disseminated skin and pulmonary involvement masquerading as multiple infantile hemangiomas

Langerhans cell histiocytosis (LCH) is a disorder characterized by abnormal proliferation of histiocytes, commonly involving the bone, skin, lungs, liver, spleen and lymph nodes. LCH is rare at birth and may easily be confused with other cutaneous lesions, thereby posing a diagnostic challenge for pediatricians. Herein, we present a patient with congenital LCH involving the skin and lungs who presented with multiple hemorrhagic vesicles with a large vascular mass at birth, closely resembling multiple infantile hemangiomas.

Source: Pediatrics and Neonatology - May 25, 2017 Category: Perinatology & Neonatology Authors: Mindy Ming-Huey Guo, Chih-Cheng Chen, Feng-Shun Chen, Hsin-Chun Huang, Mei-Yung Chung, I-Lun Chen, Shang-Hung Lin, Mei-Chen Ou-Yang, Chih-Cheng Hsiao Tags: Brief Communication Source Type: research