Tie2 as a novel key factor of microangiopathy in systemic sclerosis

The angiopoietin(Ang)/Tie2 system is a key regulator of vascular biology. The expression of membrane bound (mb) Tie2 and Ang-1 ensures vessel stability, whereas Ang-2, inducible by vascular endothelial growth ...

Source: Arthritis Research and Therapy - May 25, 2017 Category: Rheumatology Authors: Falk Moritz, Janine Schniering, J örg H. W. Distler, Renate E. Gay, Steffen Gay, Oliver Distler and Britta Maurer Source Type: research