Is there a potential of misuse for Magnolia officinalis compounds/metabolites?

ConclusionsTo the best of our knowledge, this is the first paper commenting on the possible Magnolia derivatives' potential of misuse. Magnolia's recent increase in popularity, mainly as a sedative, may be arguably due to its peculiar pharmacological properties/acceptable affordability levels/virtually worldwide favorable legal status and customers' attraction to a product being perceived as “natural” and hence somehow “safe.” Future/potent/synthetic magnolol and honokiol structural analogues could however contribute to increasing the number of synthetic GABA‐ergic/cannabimimetic misusing compounds.
Source: Human Psychopharmacology: Clinical and Experimental - Category: Psychiatry Authors: Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research