Medical News Today: Hormone replacement therapy may increase risk of hearing loss

A new, first-of-its-kind study investigates the link between hormone replacement therapy and hearing loss in menopausal and postmenopausal women.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Hearing / Deafness Source Type: news

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From hot flashes and weight gain to vaginal dryness and hormones, how much do you know about the realities and misconceptions of menopause?
Source: AARP.org News - Category: American Health Source Type: news
We examined the possible mechanism of action and found that Pyk2 deletion promotes the proteasome-mediated degradation of estrogen receptor α (ERα), but not estrogen receptor β (ERβ). As a consequence, E2 signaling via ERβ was enhanced in Pyk2-KO OBs. In addition, we found that Pyk2 deletion and E2 stimulation had an additive effect on ERK phosphorylation, which is known to stimulate cell differentiation and survival. Our findings suggest that in the absence of Pyk2, estrogen exerts an osteogenic effect on OBs through altered ERα and ERβ signaling. Thus, targeting Pyk2, in combination ...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Conclusion: Twice-yearly treatment with denosumab was associated with increased BMD among Japanese women receiving adjuvant AI therapy, regardless of the baseline characteristics or skeletal site. PMID: 30022834 [PubMed]
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: Ther Clin Risk Manag Source Type: research
CONCLUSIONS: This study confirmed the ergogenic effect of the acoustic pacesetter on a 30-minute steady state rhythmic exercise. Novelty is that the visual pacesetter too was able to increase the mechanical efficiency as the same manner than the acoustic one. The present setting adopting visual pacesetter could be used in special categories, such as the deaf or in innovative technological tools as head-mounted display devices. PMID: 30024130 [PubMed - as supplied by publisher]
Source: Journal of Sports Medicine and Physical Fitness - Category: Sports Medicine Tags: J Sports Med Phys Fitness Source Type: research
ConclusionsRCTs which investigate the impact of omega-3 supplements on vasomotor symptoms in menopausal women are scarce. A comprehensive search in a wide range of databases found only three relevant papers. Our analysis suggests that omega-3 supplements may alleviate night sweats but have no benefit in reducing hot flushes, or improving sleep quality and quality of life during the menopausal period. We recommend high quality RCTs along with a longer follow-up period to investigate this important subject, as there was insufficient evidence to conclude that omega-3 supplements are of benefit in alleviating vasomotor symptom...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Menopause, the permanent cessation of menses as a result of ovarian aging, occurs in a median age of 51 years in most populations. As longevity increases steadily worldwide, it is expected that women will spend nearly half of their lifetime beyond the menopausal transition [1]. Menopause is associated with unfavourable changes in adiposity measures, in the lipid profile, in blood pressure and in glucose metabolism, which increase the risk of cardiovascular disease later in life [2]. Although several medical approaches are successful in preventing or treating these conditions, a holistic approach encompassing diet and lifes...
Source: Maturitas - Category: Primary Care Authors: Source Type: research
Conclusion: Losartan might prevent axonal sprouting after hearing loss by blocking TGF-β signaling thereby preventing maladaptive auditory-somatosensory plasticity. PMID: 30021416 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Otorhinolaryngology - Category: ENT & OMF Tags: Clin Exp Otorhinolaryngol Source Type: research
FRIDAY, July 20, 2018 -- HDL cholesterol may be known as the " good " kind, but a new study suggests high levels of it are not always a good thing for women after menopause. The study, of nearly 1,400 postmenopausal women, found that those with...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
This article details the options, benefits and health risks associated with contraceptive use in this group.Menopause
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health Journal Article Source Type: news
We aimed to investigate the effect of omega-3 supplements on relief of vasomotor symptoms among menopausal women.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Review article Source Type: research
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