Nuclear cardiology lab cuts radiation dose by 60%

A large nuclear cardiology lab was able to reduce its average radiation dose...Read more on AuntMinnie.comRelated Reading: Cardiac MRI beats SPECT for predicting heart events Inappropriate MPI scans increase cancer risk among women Inappropriate SPECT MPI scans more common in women CCTA plus stress CT MPI boosts diagnosis of high-risk patients Hardware, software advances spark cardiac SPECT progress
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Authors: Mavriopoulou E, Zampakis P, Smpiliri E, Spyridonidis T, Rapti E, Haberkorn U, Makatsoris T, Apostolopoulos DJ Abstract OBJECTIVE: Single photon emission tomography/computed tomography (SPET/CT) is usually recommended after ambiguous whole body bone scan (WBS) findings. We investigated the value of routine 2-field ("near" whole-body) SPET/CT application in breast cancer (BC) patients. SUBJECTS AND METHODS: In this prospective study planar WBS and 2-field SPET/CT was performed in 257 consecutive BC patients referred for a bone scan. Whole body scan and SPET/CT were interpreted separately. Addit...
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
CONCLUSION: Our findings suggested that 99mTc WBS is a useful imaging modality in detecting remnant thyroid tissue, nodal and distant metastases before 131I therapy. The additional SPET/CT scan when needed in 18 cases supported the 99mTc WBS diagnosis. PMID: 30089313 [PubMed - in process]
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
AbstractRadiotheragnostics represents the systematic integration of diagnostic imaging and therapeutics using radionuclides targeting specific characteristics of tumor biology. Radioiodine (131I) is the classic radiotheragnostic agent used for the diagnosis and treatment of differentiated thyroid cancer based on sodium-iodine symporter expression in normal and neoplastic thyroid tissue. Application of radiotheragnostics principles in thyroid cancer involves using pre-ablation diagnostic scans (Dx Scans) for detection of iodine-avid regional and distant metastatic disease and patient-individualized targeted131I therapy with...
Source: Clinical and Translational Imaging - Category: Radiology Source Type: research
ConclusionFor both Lu-177-Octreotate and Lu-177-PSMA-617 therapy, BM dosimetry via sequential QSPECT imaging and a single WB-P acquisition is feasible, if this WB-P image is acquired at a late time point (48 or 72  h post-injection). The reliability of the HP can be well accepted considering the uncertainties of quantitative Lu-177 imaging and BM dosimetry using standardised organ-levelS values.
Source: EJNMMI Research - Category: Radiology Source Type: research
Abstract PURPOSE: Although inverse-planned intensity modulated radiotherapy (IMRT) and deep inspiration breath hold (DIBH) may allow for more conformal dose distributions, it is unknown whether using these technologies reduces cardiac or pulmonary toxicity of breast radiotherapy. METHODS AND MATERIALS: A randomized controlled trial compared IMRT-DIBH versus standard, free-breathing, forward-planned, three-dimensional conformal radiotherapy in patients with left-sided, node-positive breast cancer in whom the internal mammary nodal region was targeted. Endpoints included dosimetric parameters and changes in pul...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Int J Radiat Oncol Biol Phys Source Type: research
CONCLUSION: This is the first case to our knowledge describing both such lesions in one patient and the first case describing the use of 2-(3-{1-carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid (18F-DCFPyL)-PSMA PET/CT to detect IPAS. Furthermore we highlight the value of nuclear medicine diagnostic work up in complex cases. PMID: 30006647 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Nuclear Medicine - Category: Nuclear Medicine Tags: Hell J Nucl Med Source Type: research
Conclusions The high agreement between treatment response, as assessed by 99mTc-MIP-1404 SPECT/CT and BR, suggests a possible role of that imaging tool for monitoring treatment in metastatic prostate cancer. Larger, ideally prospective trials are needed to help to reveal the full potential of SPECT imaging of PSMA expression in that regard.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Original Articles Source Type: research
Publication date: 1 August 2018Source: Life Sciences, Volume 206Author(s): Christiano R.R. Alves, Daniele de P. Faria, Camila de G. Carneiro, Alexandre T. Garcez, Vanessa P. Gutierrez, Willian das Neves, Ney R. de Almeida, Yara Cury, Roger Chammas, Patricia C. BrumAbstractNoninvasive imaging using positron emission tomography/computed tomography (PET/CT) and single photon emission computed tomography/computed tomography (SPECT/CT) are considered revolutionized approaches to detect bone cancer. Both PET/CT and SPECT/CT technologies have advanced to permit miniaturization, which has provided the advantage of including animal...
Source: Life Sciences - Category: Biology Source Type: research
In this study, we prepared multifunctional microspheres loading 131I-labeled hollow copper sulfide nanoparticles and paclitaxel (131I-HCuSNPs-MS-PTX) for imaging and therapeutics of W256/B breast tumors in rats. 18F-fluordeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging detected that the expansion of the tumor volume was delayed (P
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
Publication date: 1 August 2018Source: Life Sciences, Volume 206Author(s): Christiano R.R. Alves, Daniele de P. Faria, Camila de G. Carneiro, Alexandre T. Garcez, Vanessa P. Gutierrez, Willian das Neves, Ney R. de Almeida, Yara Cury, Roger Chammas, Patricia C. BrumAbstractNoninvasive imaging using positron emission tomography/computed tomography (PET/CT) and single photon emission computed tomography/computed tomography (SPECT/CT) are considered revolutionized approaches to detect bone cancer. Both PET/CT and SPECT/CT technologies have advanced to permit miniaturization, which has provided the advantage of including animal...
Source: Life Sciences - Category: Biology Source Type: research
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