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Nuclear cardiology lab cuts radiation dose by 60%

A large nuclear cardiology lab was able to reduce its average radiation dose...Read more on AuntMinnie.comRelated Reading: Cardiac MRI beats SPECT for predicting heart events Inappropriate MPI scans increase cancer risk among women Inappropriate SPECT MPI scans more common in women CCTA plus stress CT MPI boosts diagnosis of high-risk patients Hardware, software advances spark cardiac SPECT progress
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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A 39-year-old woman with papillary thyroid cancer underwent 131I therapy after thyroidectomy. Posttherapeutic 131I whole-body scan accidentally showed symmetric “hot spots” in the pelvic region beyond known bone metastases. SPECT/CT was immediately added and revealed metal artifacts with 131I accumulation in the nearby uterus. Further inquiry discovered that she underwent tubal ligation 19 years ago. Our case demonstrates that 131I accumulation can occur at the site of oviducts many years after tubal ligation, which should be distinguished from 131I-avid metastases.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
In this study, we prepared multifunctional microspheres from 131I-labeled hollow copper sulfide nanoparticles loaded with paclitaxel (131I-HCuSNPs-MS-PTX) for imaging and therapeutics of W256/B breast tumors in rats. 18F-fluordeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging detected that the expansion of the tumor volume was delayed (P<0.05) following intra-tumoral (i.t.) injection with 131I-HCuSNPs-MS-PTX plus near-infrared (NIR) irradiation. The immunohistochemical analysis further confirmed the anti-tumor effect. The single photon emission computed tomography (SPECT)/photoacous...
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
Conclusion: Radioembolization with 166Ho-microspheres induced a tumor response with an acceptable toxicity profile in salvage patients with liver metastases.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Clinical Source Type: research
CONCLUSION: Residual nodal metastasis following initial surgical treatment for regionally advanced differentiated thyroid cancer is rather common on highly sensitive 131-I scans with SPECT/CT and is due to both unrecognized nodal involvement preoperatively and incomplete removal of metastatic lymph nodes during compartment-orientated nodal dissection. The surgical management of high-risk DTC should include preoperative imaging to evaluate for nodal metastases in the central and lateral neck and compartment-orientated nodal dissection of involved compartments. Attention should be given to complete dissection in levels VI, I...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Authors: Ceci F, Castellucci P, Fanti S Abstract As precision medicine evolves, the contribution of molecular imaging to the management of prostate cancer (PCa) patients, especially for Positron Emission Tomography (PET) imaging, is gaining importance. Highly successful approaches to measure the expression of the prostate specific membrane antigen (PSMA) have been introduced recently. PSMA, the glutamate carboxypeptidase II (GCP-II), is a membrane bound metallo-peptidase that is overexpressed in 90-100% of PCa cells. Due to its selective over-expression, PSMA is a reliable tissue marker for prostate cancer and is c...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Conclusions MIP-1404 SPECT/CT has a high accuracy and low interobserver variability in the diagnosis of PC and allows detection of lymph node and bone metastases in a significant proportion of as yet untreated PC patients. TUprostate is correlated with Gleason score and PSA serum concentration and allows prediction of the occurrence of lymph node and bone metastases with moderate accuracy at primary staging.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Original Articles Source Type: research
We present a case with postoperative inflammatory aortobiiliac bypass graft which was misdiagnosed as AGI based on intense 18F-FDG activity seen at PET/CT imaging. Rationale: 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) has the potential to become an important imaging tool for the diagnosis of suspected aortoiliac bypass graft infection (AGI). Patient concerns: A 76-year-old man presented with incidental findings of intense 18F-FDG activity in previous operation site of aortobiiliac bypass graft in the initial staging of small cell lung cancer (SCLC). Diagnoses: Based...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
AbstractRationale:Iodine-131 (I-131) is a sensitive marker for the detection of differentiated thyroid cancer (DTC). I-131 whole-body scintigraphy (WBS) has been used widely in evaluation of DTC patient. However, I-131 WBS exists many false-positive uptake of I-131 because radioiodine uptake can also be seen in healthy tissue or in a variety of benign and malignant non-thyroidal tumors.Patient concerns:A 44-year-old woman with a papillary thyroid carcinoma for the purpose of ablation therapy after a total thyroidectomy. I-131 WBS showed intensive uptake by thyroid remnant. Meanwhile, a focus of increased activity was seen ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
We present a case of a synchronous papillary thyroid cancer and a follicular variant of non-Hodgkin lymphoma and discuss the possible diagnostic and treatment dilemmas.Diagnosis:A 48-year-old female was reffered to our hospital with diagnosis „thyroid cancer“. Due to a history compatable of synchronous lymphoproliferative disease we performed a computed tomography, which revealed multiple enlarged lymph nodes in the neck, mediastinum, axilla and abdomen.Interventions:A total thyroidectomy with dissection of the central compartment was performed. The microscopic examination of thyroid gland revealed multifocal p...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Conclusion The SWMD20% and FV20 of FL using 20% of the maximum SPECT count as the threshold may be better predictors for the risk of RP.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research
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