Genetic factors influencing the reduction of central corneal thickness in disorders affecting the eye.

CONCLUSIONS: Specific sequence variants in COL8A2, PRDM5 and ZNF469, COL5A1 and ZNF469, and COL5A1 and COL5A2 could probably contribute to a CCT reduction in POAG, BCS, KTCN, and EDS, respectively. Similar sequence variants and phenotypes were identified and assessed in more than one disease. PMID: 28453375 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28453375?dopt=Abstract

Source: Ophthalmic Genetics - April 30, 2017 Category: Opthalmology Tags: Ophthalmic Genet Source Type: research