Could Cocaine Exposure Mitigate Edema Formation in Spontaneous Intracerebral Hemorrhage? (P2.279)

Conclusions:Our study demonstrates that cocaine was associated with higher ICH volumes, with comparatively lower volumes of PHE. Due to small sample size, there, was insufficient power to draw conclusions regarding the effect of cocaine exposure on PHE or ICH volume; nevertheless, the difference in the ICH: PHE ratio was significant. The mechanism for lower relative edema volume remains unclear and a large prospective study is needed to assess the roles of vasoconstrictors in preventing edema expansion in ICH.Disclosure: Dr. Singh has nothing to disclose. Dr. Albright has nothing to disclose. Dr. Pennington has nothing to disclose. Dr. Gropen has nothing to disclose. Dr. Shapshak has nothing to disclose.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Singh, M., Albright, K., Pennington, A., Gropen, T., Shapshak, A. H. Tags: Intracerebral Hemorrhage Source Type: research