Increasing Antibiotic Resistance in Shigella spp. in NYC Increasing Antibiotic Resistance in Shigella spp. in NYC

A new report of shigellosis cases in New York City provides insight into the increasing resistance to antibiotics commonly prescribed to treat the infection.Emerging Infectious Diseases
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Infectious Diseases Journal Article Source Type: news

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Publication date: 23–29 March 2019Source: The Lancet, Volume 393, Issue 10177Author(s): Tony Kirby
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionsInfection control priorities in hospitals should include preventing surgical site infections, pneumonia, bloodstream infections, and urinary tract infections. These results may help to delineate the requirements for infection prevention and control in acute care hospitals.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
Abstract HIV-positive patients are treated with various antiretroviral-containing drug combinations to control their underlying disease, which may also be combined with drugs aimed to manage independent or secondary comorbidities. This can expose patients to drug-drug interactions (DDIs) that may lead to suboptimal drug exposure, an increased risk of therapeutic failure or poor tolerability, and a need to adopt alternative therapeutic strategies. Although such undesired responses to pharmacological therapies can be appropriately managed in some situations, the fact that the available information is usually incompl...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
PMID: 30899118 [PubMed - in process]
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
Abstract The goal of this report was to propose a model, wherein synergy between the B-cell antigen receptor (BCR) and toll-like receptor (TLR) signaling is involved in the selection of the B-cell precursors of HIV-1 broadly neutralizing antibodies (bnAbs) with long heavy chain complementarity determining regions 3, from immature/transitional B cells. The model predicts the involvement of Ab/HIV-1 complexes in a way that Ab from the complex binds both BCRs and HIV-1, while on internalization of HIV-1 TLR ligands such as CpG motifs interacts with TLR9. The result of BCR and TLR9 orchestrated signaling is a formatio...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with ...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
Publication date: December 2017 Source:The Lancet Global Health, Volume 5, Issue 12 Author(s): Kirkby D Tickell, Rebecca L Brander, Hannah E Atlas, Jeffrey M Pernica, Judd L Walson, Patricia B Pavlinac Background Shigella infections are a leading cause of diarrhoeal death among children in low-income and middle-income countries. WHO guidelines reserve antibiotics for treating children with dysentery. Reliance on dysentery for identification and management of Shigella infection might miss an opportunity to reduce Shigella-associated morbidity and mortality. We aimed to systematically review and evaluate Shigella-associated...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Shigella infection is becoming increasingly resistant to certain antimicrobial agents. What's the best course of action for this high-risk population?Emerging Infectious Diseases
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Infectious Diseases Journal Article Source Type: news
Shigella flexneri is an emerging pathogen in men who have sex with men (MSM); recent outbreaks related to sexual practices have been noted in this population in the UK and other developed countries. While the majority of cases of shigellosis present with gastroenteritis, some vulnerable patients with underlying immunosuppression can develop complications like bacteraemia and may present atypically as an acute surgical emergency. This case report highlights such a case of S. flexneri bacteraemia in a man who had sex with men.
Source: International Journal of STD and AIDS - Category: Global & Universal Authors: Tags: Case reports Source Type: research
Conclusions HIV-positive MSM infected with S flexneri 3a used social media to meet sexual partners for unprotected sex mainly at sex parties. The potential for the transmission of S flexneri, HIV and other infections is clear. MSM need to be aware of the effect that chemsex drugs have on their health.
Source: Sexually Transmitted Infections - Category: Sexual Medicine Authors: Tags: Editor's choice, Drugs: infectious diseases, HIV/AIDS, HIV / AIDS, Gonorrhoea, HIV infections, Health education Epidemiology Source Type: research
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