Genetics: ACVR1 mutations—a key piece in paediatric diffuse glioma

Nature Reviews Clinical Oncology 11, 300 (2014). doi:10.1038/nrclinonc.2014.74 Author: M. Teresa Villanueva High-grade glioma—or high-grade astrocytoma (HGA)—have a devastating prognosis, with survival ranging from 20–30% for tumours outside the brainstem, and less than 10% for diffuse intrinsic pontine gliomas (DIPGs), which arise in the brainstem and are found almost exclusively in children. Aside from radiotherapy, there is
Source: Nature Clinical Practice Oncology - Category: Cancer & Oncology Authors: Tags: Research Highlight Source Type: research