Varying Correlation Between 18F-Fluorodeoxyglucose Positron Emission Tomography and Dynamic Contrast-Enhanced MRI in Carotid Atherosclerosis: Implications for Plaque Inflammation [Brief Reports]

Conclusions— The correlation between 18F-fluorodeoxyglucose positron emission tomography and dynamic contrast-enhanced MRI measurements varied with clinical conditions, pointing to a complex interplay between macrophages and neovessels under different pathophysiological conditions. The moderate correlation shown only in symptomatic plaques indicates the presence of acute plaque inflammation with increased metabolic activity and cytokine production by inflammatory cells.

http://stroke.ahajournals.org/cgi/content/short/45/6/1842?rss=1

Source: Stroke - May 27, 2014 Category: Neurology Authors: Wang, J., Liu, H., Sun, J., Xue, H., Xie, L., Yu, S., Liang, C., Han, X., Guan, Z., Wei, L., Yuan, C., Zhao, X., Chen, H. Tags: Pathophysiology, Imaging, Carotid Stenosis, Mechanism of atherosclerosis/growth factors Brief Reports Source Type: research