SOCS1 Regulates Apoptosis and Inflammation by Inhibiting IL-4 Signaling in IL-1 β-Stimulated Human Osteoarthritic Chondrocytes.

In conclusion, IL-4 signaling plays a crucial role in the regulatory functions of SOCS1 in apoptosis and inflammation in human osteoarthritic chondrocytes. These findings provide a potential therapeutic target for the clinical treatment of OA.
PMID: 28373981 [PubMed - in process]

Source: Biomed Res - April 5, 2017 Category: Research Authors: He Q, Sun C, Lei W, Ma J Tags: Biomed Res Int Source Type: research