Bisphosphonate-Related Osteonecrosis and Metastasis Within the Same Site of the Jaw: Expected for Multiple Myeloma, But Unusual for Breast Cancer

I want to congratulate Corsi et  al1 for the case report in which they presented a patient with breast cancer treated with zoledronic acid for skeletal metastasis in which a clinical diagnosis of bisphosphonate-related osteonecrosis of the jaw (BP-related ONJ) was made and histologic examination of the resected mandibular segment disclosed synchronous osteonecrosis and breast cancer metastasis. As the authors stated, this metastatic presentation in the mandibular region is unusual for breast cancer because bone metastases in breast cancer commonly occur in the spine, pelvis, ribs, and sternum.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Letter to the editor Source Type: research