East Africa: Study Links Nodding Syndrome to River Blindness Parasite Worm
[East African] A team of experts researching the mysterious Nodding syndrome has concluded that the disease may be caused by the immune system's response to a parasitic worm that also causes river blindness.
ConclusionsNational programs need to regularly monitor and evaluate the performance and progress of their interventions, while envisaging the complete elimination of onchocerciasis from their territory. Factors hindering the targeted goal of interruption of parasite transmission need to be identified and remedial actions should be taken. If possible and appropriate, ATSs need to be implemented to accelerate disease elimination by 2025.
ConclusionThe culture system we have established forO.volvulus young adult worms offers a promising new platform to advance drug discovery against the human filarial parasite,O.volvulus and thus supports the continuous pursuit for effective macrofilaricidal drugs. However, thisin vitro culturing system will have to be further validated for reproducibility before it can be rolled out as a drug screen for decision making in macrofilaricide drug development programs.
Onchocerciasis, or river blindness, is a dermal filariasis caused by infection with the nematode parasite Onchocerca volvulus, transmitted to humans through the bites of blackflies of the genus Simulium. Despite ...
The new data could help identify treatments for diseases ranging from river blindness to schistosomiasis.
ConclusionKeen observation on the part of physicians is mandatory during the administration of ivermectin for quick recognition and prevention of this adverse drug reaction.
(Scripps Research Institute) Scientists at Scripps Research have developed a urine diagnostic to detect the parasitic worms that cause river blindness, also called onchocerciasis, a tropical disease that afflicts 18 to 120 million people worldwide.
Conclusions/SignificanceWe report for the first time the anti-onchocercal activities of these locally consumed medicinal plants and lantadene A, a potential lead for further development as an onchocerciasis cure.
Conclusions/SignificanceWHO criteria have been met, therefore MDA in Bioko Island can be stopped. Three years of post-treatment surveillance should be implemented to identify any new occurrences of exposure or infection.
Customized iPhones are just one example of devices that can be used to combat health threats in developing countries. They are helping scientists in California and Cameroon attack the parasite that causes river blindness, an African scourge.Kaiser Health News
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 235 and infectious diseases / animal theme. Readers can subscribe to FFFF RSS or subscribe to the FFFF weekly EMAIL Question 1: What tropical disease will give you Leopard or Lizard skin? + Reveal the Funtabulous Answer expand(document.getElementById('dde...