Cobalt Chloride Enhances the Stemness of Human Dental Pulp Cells

Hypoxia is a factor in controlling stem cell stemness. We investigated if cobalt chloride (CoCl2), a chemical agent that mimics hypoxia in  vitro, affected human dental pulp cell (hDPC) stemness by examining cell proliferation, stem cell marker expression, and osteogenic differentiation.

Source: Journal of Endodontics - March 23, 2017 Category: Dentistry Authors: Kantaporn Laksana, Sireerat Sooampon, Prasit Pavasant, Wannakorn Sriarj Tags: Basic Research Source Type: research