Defective natural killer cell activity in a mouse model of eczema herpeticum

Patients with atopic dermatitis (AD) are susceptible to several viruses, including herpes simplex virus (HSV). Some patients experience 1 or more episodes of a severe skin infection caused by HSV termed eczema herpeticum (EH). There are numerous mouse models of AD, but no established model exists for EH.

Source: Journal of Allergy and Clinical Immunology - July 29, 2016 Category: Allergy & Immunology Authors: Yuko Kawakami, Tomoaki Ando, Jong-Rok Lee, Gisen Kim, Yu Kawakami, Tae Nakasaki, Manando Nakasaki, Kenji Matsumoto, Youn Soo Choi, Toshiaki Kawakami Tags: Mechanisms of allergy and clinical immunology Source Type: research