IGF-I and IGFBP-3 levels and their correlations with carcinoembryonic antigen in colorectal cancer patients

Conclusions IGF-I/IGFBP-3 ratio seems to be increased in the colorectal cancer patients. When considered with the moderate correlation levels of these peptides with CEA, this increase in IGF-I/IGF-BP3 ratio may be useful in monitoring carcinogenesis in colorectal cancer patients among with CEA but more detailed and extensive studies in larger study groups needed to be carried out.
Source: Alexandria Journal of Medicine - Category: Journals (General) Source Type: research