Meningococcal disease – Togo

Since 1 January 2017, 201 suspected cases of meningitis with 17 deaths were reported by 19 health districts. In week 2, the district of Akebou which is part of the Plateau Region issued an alert after four cases of meningitis were reported. In week 4, the epidemic threshold was reached with nine cases and an attack rate of 12.4 per 100 000 inhabitants. From 2 January to 12 February 2017, 48 suspected meningitis cases with three deaths were reported (case fatality rate of 6.3%). Of these, 14 specimens were confirmed as Neisseria meningitidis serogroup W by PCR.
Source: WHO Disease Outbreaks - Category: Infectious Diseases Tags: news Source Type: news

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ConclusionsVillage-wide antibiotic prophylaxis should be considered and tested further as a response against outbreaks of meningococcal meningitis in the Meningitis Belt, as a supplement to reactive mass vaccination.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
gnolo Serratia marcescens belongs to the family Enterobacteriaceae, which is commonly found in water, soil, animals, insects, plants. Although S. marcescens displays relatively low virulence, it causes nosocomial infections and outbreaks in severely immunocompromised or critically ill patients, particularly in settings such as intensive care units (ICUs), especially neonatal units (NICUs). This microorganism gives rise to a wide range of clinical manifestations in newborns: from asymptomatic colonization to keratitis, conjunctivitis, urinary tract infections, pneumonia, surgical wound infections, sepsis, bloodstream in...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
S, Bidet P Abstract We developed a multiplex PCR method based on Multiple-Locus Variable-number of tandem repeats (VNTR)-Analysis (MLVA) designed for rapid typing of E. coli and Shigella isolates The method amplifying seven VNTRs doesn't require sequencing capillary nor fluorescent dyes. Amplification products are simply loaded on a standard agarose gel for electrophoresis and banding patterns are analyzed visually. We evaluated the method on 220 strains belonging to different collections: ECOR collection (n=72), O1:K1 isolates causing neonatal meningitis (n=38), extended-spectrum beta-lactamase-producing fecal i...
Source: Applied and Environmental Microbiology - Category: Microbiology Authors: Tags: Appl Environ Microbiol Source Type: research
[Vanguard] Towards ending the series of outbreaks of Lassa fever, Monkeypox, yellow fever, cholera, meningitis, Ebola and other epidemic diseases in Nigeria, the Nigeria Centre for Disease Control, NCDC, and the Private Sector Health Alliance of Nigeria, PHN, have launched the Alliance for Epidemic Preparedness and Response, A4EPR.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
We described the outbreak, strengthened surveillance, improved laboratory testing and managed data which informed decision making.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: UMP. 337 Source Type: research
In conclusion, we developed and validated a predictive model that can be used in meningitis surveillance system in Iran. However, further research is needed to use the model in practice with different pathogen types of bacterial meningitis in order to proper antimicrobial therapy planning. PMID: 29968622 [PubMed - in process]
Source: Studies in Health Technology and Informatics - Category: Information Technology Tags: Stud Health Technol Inform Source Type: research
Abstract In February and March 2016, four cases of serogroup B invasive meningococcal disease (IMD) occurred over 3 weeks in a small area north of Lyon in the Auvergne-Rhône-Alpes region, France. There were no deaths but two cases had sequelae. This community outbreak was caused by a rare meningococcal strain of the clonal complex ST-32, covered by the 4CMenB/Bexsero vaccine. The incidence rate for serogroup B IMD in this area was 22.5 per 100,000 inhabitants, which is above the epidemic threshold (10/100,000). The number of cases observed was significantly higher than expected in the age group of 0-24 year-...
Source: Euro Surveill - Category: Infectious Diseases Authors: Tags: Euro Surveill Source Type: research
ConclusionsVillage-wide distribution of single-dose oral ciprofloxacin within 72 hours of case notification reduced overall meningitis AR. Distributions of ciprofloxacin could be an effective tool in future meningitis outbreak responses, but further studies investigating length of protection, effectiveness in urban settings, and potential impact on antimicrobial resistance patterns should be carried out. Trial registrationClinicalTrials.gov NCT02724046
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
Abstract Meningococcal disease is a serious public health threat given the seriousness of the illness, its disabling sequelae and its potential for epidemic spread. The disease is a concern during mass gatherings which provide conditions that facilitate transmission of infectious agents including Neisseria meningitidis. Implementation of appropriate meningococcal disease preventive measures during at-risk mass gatherings is crucial to prevent illness and outbreaks which may result in significant morbidity and mortality as well as local and international spread of the disease. These preventive measures should be in...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
[Vanguard] INSURANCE products to facilitate financial responses to outbreaks of diseases such as Ebola, Meningitis, and Lassa fever in Nigeria and 29 other Africa countries are underway. An agency of the African Union, the African Risk Capacity, ARC, in a statement, weekend, said that it is working with West, East and Central African countries to determine their epidemic risks and select pathogens to be covered.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
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