Angiotensin‐(1‐7) Induces Cerebral Ischemic Tolerance by Promoting Brain Angiogenesis in a Mas/eNOS‐Dependent Pathway

Conclusions and implicationsOur results provide the first evidence that Ang‐(1‐7) promotes brain angiogenesis via a Mas/eNOS‐dependent pathway, which enhances tolerance against subsequent cerebral ischemia. These findings highlight brain Ang‐(1‐7)/Mas signaling as a potential target in stroke prevention.

Source: British Journal of Pharmacology - May 13, 2014 Category: Drugs & Pharmacology Authors: Teng Jiang, Jin‐Tai Yu, Xi‐Chen Zhu, Qiao‐Quan Zhang, Meng‐Shan Tan, Lei Cao, Hui‐Fu Wang, Jie Lu, Qing Gao, Ying‐Dong Zhang, Lan Tan Tags: Research Paper Source Type: research