Bioinformatics in the Identification of Novel Targets and Pathways in Neurodegenerative Diseases

AbstractPurpose of ReviewNeurodegenerative diseases are a heterogeneous group of complex conditions that lead to progressive degeneration or death of neurons. The economical and societal costs of these diseases are increasing rapidly, so there is an urgent need to find new solutions to remedy the situation. Understanding these diseases on a molecular pathway level could lead to development of better biomarkers and treatments, but the massive amounts of data involved makes this a challenge.Recent FindingsBioinformatics approaches can be used to manage and analyze data from the current high-throughput research technologies and provide means for novel discoveries in the field of neurodegenerative diseases.SummaryThis review introduces different bioinformatics approaches used to identify and study molecular targets and pathways, using examples from recent neurodegenerative diseases research.

Source: Current Genetic Medicine Reports - February 17, 2017 Category: Genetics & Stem Cells Source Type: research