Promoting motor recovery in patients with stroke enhancing cerebellar cortical plasticity: a randomized double blinded controlled repetitive TMS trial

Introduction: The cerebellum is known to be strongly implicated in the functional reorganization of motor networks in stroke patients. In animal models of stroke it has been shown that stimulation of cerebellar-cortical networks plays a major role for motor recovery. Repetitive transcranial magnetic stimulation (rTMS) can be used to enhance adaptive processes and prevent those potentially maladaptive in stroke recovery. In this randomized, double blind, sham-controlled trial we investigated the efficacy of cerebellar intermittent theta burst stimulation (iTBS) coupled with intensive physical therapy (PT) in promoting functional recovery in patients with hemispheric stroke.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research