The value of adaptive preoperative radiotherapy in management of soft tissue sarcoma.

CONCLUSION: GTV expansion of >1cm during RT may result in target underdosage independent of RT technique. ART applied offline for TV increases >1cm is a practical adaptive strategy to ensure tumour coverage during RT. TV shrinkage may allow for normal tissue sparing, which should be investigated prospectively.
PMID: 28169043 [PubMed - as supplied by publisher]

Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 2, 2017 Category: Radiology Authors: Dickie C, Parent A, Griffin AM, Wunder J, Ferguson P, Chung PW, Craig T, Sharpe M, Becker N, Shultz D, Catton CN, O'Sullivan B Tags: Radiother Oncol Source Type: research