Cat Scratch Disease

Cat scratch disease is an infection transmitted by cat scratches and bites. The lesion is usually small and less than 1 cm in length. It is normally a benign, self-limiting illness lasting for about 6-12 weeks. It is caused by an exposure to bartonella henselae bacteria. Scratches or bites from an infected cat can cause symptoms in people including swollen and draining lymph nodes, fever, fatigue and headache. Swollen, tender, or hard lymph nodes could be confused with a soft tissue tumor. Regional Lymphadenopathy (main clinical feature) These areas of lymph node concentration include cervical nodes, axillary nodes, cubital (epitrochlear nodes), and inguinal nodes. Timeline of events The timeline of events leading to cat scratch disease first begins with a bite or scratch. Within one week, there is the development of a skin lesion in about 50% of the patients. There will be noticeably enlarged lymph nodes within the first two weeks. Swollen lymph nodes with no other etiology and a scratch or bite from being in contact with a cat, could suggest the presence of cat scratch disease. Symptoms are self-limiting and can vary from mild to severe, lasting for several weeks. The physician should check for elevated sedimentation rate and C-Reactive protein (CRP), both are blood tests that could show infection. A positive skin test for cat-scratch disease is important for establishing the diagnosis. Treatment includes doxycycline, ciprofloxacin and azithromycin. It ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

Related Links:

In this study, we report that the Protium javanicum methanol extract (Pj-ME) plays an important role in suppressing nitric oxide (NO) levels without cytotoxicity. The effect of Pj-ME in LPS-induced expression leads to reduced inflammatory cytokine expression, specifically inducible nitric oxide synthase (iNOS), cyclooxygenase (COX-2), and tumor necrosis factor (TNF-α). Pj-ME significantly inhibited LPS-induced protein expression of the nuclear factor-kappa B (NF-κB) signaling pathway in a time-dependent manner. Syk and Src were identified as putative signaling molecules of Pj-ME-mediated anti-inflammatory activ...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Publication date: July 2019Source: Microchemical Journal, Volume 148Author(s): F. Spataro, N. Ademollo, T. Pescatore, J. Rauseo, L. PatroleccoAbstractEndocrine disrupting compounds (EDCs) and pharmaceutical residues are environmental ubiquitous contaminants of particular concern due to their possible ecotoxicological effects on aquatic ecosystems. In this work, the occurrence and fate of six antibiotics (amoxicillin, ciprofloxacin, tylosin, erithromycin, sulfamethoxazole and chlortetracycline) and four phenolic endocrine disrupting compounds (EDCs, i.e. bisphenol A, 4-nonylphenol, nonylphenol mono- and di-ethoxylate) in th...
Source: Microchemical Journal - Category: Chemistry Source Type: research
BACKGROUND The development of procedural skills is necessary for medical students. Computer-based video instruction (CBVI) increases knowledge and procedural skills. OBJECTIVE This pilot study's aim was to investigate the usefulness of CBVI in dermatologic procedure training for medical students and secondarily assess students' overall perception of the field of dermatology. METHODS Twenty-nine first- and second-year medical students were randomly assigned to the CVBI group or control group, in addition to in-person instructor demonstration of shave and punch biopsies using fresh cadaver tissue. Blinded evaluators ...
Source: Dermatologic Surgery - Category: Dermatology Tags: Original Article Source Type: research
This study concludes that the developed CxLSENPs might be employed as strong antimicrobial and antioxidant agents for treating lung infection or interstitial lung diseases.Graphical Abstract
Source: Journal of Photochemistry and Photobiology B: Biology - Category: Speech-Language Pathology Source Type: research
Caplacizumab-yhdp (Cablivi) is the first drug specifically indicated for acquired thrombotic thrombocytopenic purpura, a rare and potentially life-threatening blood clotting disorder. It is prescribed in combination with plasmapheresis and immunosuppressive therapy.The drug carries a warning that severe bleeding can occur with use, although the most common adverse effects are headache and minor bleeding from the nose or gums.Caplacizumab-yhdp is given initially as an iv bolus and then as a subcutaneous injection along with plasmapheresis.
Source: AJN - Category: Nursing Tags: Drug Watch Source Type: research
AbstractTo investigate the clinical manifestation, disease course, and prognosis of migraine patients with or without personality disorders. This cross-sectional study evaluated 61 patients with migraine diagnosed according to the criteria of the International Headache Society (IHS). Personality disorders were assessed with the Structured Clinical Interview for DSM-IV (SCID-II). Migraine severity was assessed with the Headache Impact Test-6 (HIT-6). We also used a structured clinical interview to diagnose comorbid mood disorders. Of the 61 patients, 20 (32.8%) had personality disorders. Personality disorders included obses...
Source: Acta Neurologica Belgica - Category: Neurology Source Type: research
ConclusionWe used DF6-9-9T.B hiPSC cell line, reprogrammed skin fibroblasts and peripheral blood mononuclear cells to develop our image processing parameters and picking and weeding protocols. To define and quantify critical quality attributes (CQAs) of “completely” reprogrammed iPS cells in systematic repeatable and reproducible manner, the Cell XTMPlatform is integrated with ColonyzeTM4.0, a very user-friendly WindowsTM-based automated quantitative cell and colony analysis software. The principles and nomenclature enabling this approach are outlined in ASTM Standard F2944-12. To automate manipulation of iPS c...
Source: Cytotherapy - Category: Cytology Source Type: research
This article presents the common and rare imaging features of regional and multiorgan cat scratch disease using a multimodality imaging approach. We highlight key characteristics so that they may become more recognizable to the radiologist.
Source: Contemporary Diagnostic Radiology - Category: Radiology Tags: Article Source Type: research
This article describes the case of an atypical presentation of CSD in a 52-year-old patient with acute unilateral loss of vision and headache without fever or lymphadenopathy. Funduscopic examination showed an optic disc swelling and macular star exsudates, pathognomonic for infectious neuroretinitis. A Bartonella henselae infection was confirmed serologically. Systemic antibiotic combination therapy was initiated with doxycycline and rifampicin for 6 weeks resulting in good morphological and functional results. A Bartonella neuroretinitis should be considered in the differential diagnosis of patients w...
Source: Der Ophthalmologe - Category: Opthalmology Authors: Tags: Ophthalmologe Source Type: research
A previously healthy 5-year-old girl was referred following a spiking fever for 8 days accompanied by abdominal pain, fatigue, and headache. Physical examination was unremarkable. Initial laboratory evaluation revealed a white blood cell count of 12 100/mm3 (normal ranges, 4000-10 000/mm3) and C-reactive protein of 12.06 mg/dL (normal value,
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Insights and Images Source Type: research
More News: Azithromycin | Cat Scratch Disease | Cipro | Ciprofloxacin | Doxycycline | Headache | Migraine | Skin | Skin Biopsy | Websites | Zithromax