Chronic kidney disease: Mechanisms of APOL1-associated renal disease

Nature Reviews Nephrology 13, 62 (2017). doi:10.1038/nrneph.2016.175 Author: Ellen F. Carney Mutations in APOL1 are associated with an increased risk of renal disease and are found at a high frequency in people of African ancestry. Two recent studies used transgenic Drosophila melanogaster models to investigate the molecular mechanisms that underlie APOL1-associated renal disease.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research