Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeruginosa in human microbiota-associated mice

ConclusionAcute intestinal inflammation facilitates infection of the vertebrate host with MDR bacteria includingP. aeruginosa and might also pose particularly hospitalized patients at risk for acquisition. Since acuteT. gondii induced inflammation might mask immunopathology caused byP. aeruginosa, a subacute or chronic inflammation model might be better suited to investigate the potential role ofP. aeruginosa infection in the aggravation of intestinal disease.
Source: Gut Pathogens - Category: Microbiology Source Type: research