Radiotherapy-induced vaginal fibrosis in cervical cancer survivors.

CONCLUSIONS: We found drastic differences in the vaginal wall between the irradiated cervical cancer survivors and the controls, indicating that radiotherapy-induced vaginal symptoms are mediated by connective tissue fibrosis and elastosis. Our results also support that patients treated with external radiation have the highest risk of developing vaginal fibrosis with impairment of their sexual health.
PMID: 28084859 [PubMed - as supplied by publisher]

Source: Acta Oncologica - January 12, 2017 Category: Cancer & Oncology Authors: Hofsjö A, Bohm-Starke N, Blomgren B, Jahren H, Steineck G, Bergmark K Tags: Acta Oncol Source Type: research