Apelin targets gut contraction to control glucose metabolism via the brain

Conclusions
Here, we identify a novel mode of communication between the intestine and the hypothalamus that controls glucose utilisation. Moreover, our data identified oral apelin administration as a novel potential target to treat metabolic disorders.

Source: Gut - January 5, 2017 Category: Gastroenterology Authors: Fournel, A., Drougard, A., Duparc, T., Marlin, A., Brierley, S. M., Castro, J., Le-Gonidec, S., Masri, B., Colom, A., Lucas, A., Rousset, P., Cenac, N., Vergnolle, N., Valet, P., Cani, P. D., Knauf, C. Tags: Open access Neurogastroenterology Source Type: research