[Evaluation of malaria Rapid Diagnostic Test Optimal-IT ® pLDH along the Plasmodium falciparum distribution limit in Mauritania].

[Evaluation of malaria Rapid Diagnostic Test Optimal-IT® pLDH along the Plasmodium falciparum distribution limit in Mauritania]. Bull Soc Pathol Exot. 2016 Dec 29;: Authors: Ba H, Ahouidi AD, Duffy CW, Deh YB, Diedhiou C, Tandia A, Diallo MY, Assefa S, Lô BB, Elkory MB, Conway DJ Abstract Performance of the malaria Rapid Diagnostic Test (RDT) OptiMal-IT® was evaluated in Mauritania where malaria is low and dependent on a short transmission season. Slide microscopy was considered as the reference method of diagnosis. Febrile patients with suspected malaria were recruited from six health facilities, 3 urban and 3 rural, during two periods (December 2011 to February 2012, and August 2012 to March 2013). Overall, 780 patients were sampled, with RDT and thick blood film microscopy results being obtained for 759 of them. Out of 774 slides examined, of which 200 were positive, P. falciparum and P. vivax mono-infections were detected in 63.5% (127) and 29.5% (59), while P. falciparum/P. vivax coinfections were detected in 7% (14). Both species were observed in all study sites, although in significantly different proportions. The proportions of thick blood film and OptiMal-IT® RDT positive individuals was 26.3% and 30.3% respectively. Sensitivity and specificity of OptiMal-IT® RDT were 89% [95% CI, 84.7-93.3] and 91.1% [88.6-93.4]. Positives and negative predictive values were 78.1% [72.2-83.7] and 95.9% [94.1-97.5]. These diagnostic val...
Source: Bulletin de la Societe de Pathologie Exotique - Category: Tropical Medicine Tags: Bull Soc Pathol Exot Source Type: research