Description of Ictal HFO Mapping in Patients with Both Temporal and Extratemporal Seizure Focus.

Description of Ictal HFO Mapping in Patients with Both Temporal and Extratemporal Seizure Focus. Neurol Res Int. 2016;2016:5380907 Authors: Ochoa JG, Rusyniak WG Abstract Objective. Review presurgical use of ictal HFO mapping to detect ictal activation areas with dual seizure focus in both the temporal and extratemporal cortex. Methods. Review of consecutive patients admitted to the University of South Alabama Epilepsy Monitoring Unit (SouthCEP) between January 2014 and October 2015, with suspected temporal lobe epilepsy and intracranial electrode recording. Ictal HFO localization was displayed in 3D reconstructed brain images using the patient's own coregistered magnetic resonance imaging (MRI) and computed tomography (CT) with the implanted electrodes. Results. Four of fifteen patients showed evidence of extratemporal involvement at the onset of the clinical seizures. Ictal HFO mapping involving both frontal and temporal lobe changed the surgical resection areas in three patients where the initial surgical plan included only the temporal lobe. Resection of the ictal HFO at the onset of the seizure and the initial propagation region was associated with seizure freedom in all patients; follow-up period ranged from 12 to 25 months. Significance. Extratemporal ictal involvement may not have clinical manifestations and may account for surgical failure in temporal lobe epilepsy. Ictal HFO mapping is useful to define the ictal cortical network and may help det...
Source: Neurology Research International - Category: Neurology Tags: Neurol Res Int Source Type: research

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Authors: Jobst BC, Gonzalez-Martinez J, Isnard J, Kahane P, Lacuey N, Lahtoo SD, Nguyen DK, Wu C, Lado F Abstract Insular seizures are great mimickers of seizures originating elsewhere in the brain. The insula is a highly connected brain structure. Seizures may only become clinically evident after ictal activity propagates out of the insula with semiology that reflects the propagation pattern. Insular seizures with perisylvian spread, for example, manifest first as throat constriction, followed next by perioral and hemisensory symptoms, and then by unilateral motor symptoms. On the other hand, insular seizures may ...
Source: Epilepsy Currents - Category: Neurology Tags: Epilepsy Curr Source Type: research
We report two cases of cerebellar lesions who presented with hemifacial seizures since the neonatal period and were refractory to antiepileptic drugs (AEDs). Both inter-ictal and ictal EEGs were non-contributory. Magnetic resonance imaging (MRI) showed a lesion in the cerebellum, in proximity to cerebellar peduncle in both the patients. (18) F-fluorodeoxyglucose–positron emission tomography (FDG-PET) and ictal single photon emission computed tomography (SPECT) showed focal hypermetabolism and hyperperfusion respectively, corresponding to the lesion on MRI in both the cases. Intraoperative electrocorticography showed ...
Source: Neurology India - Category: Neurology Authors: Source Type: research
ConclusionsTraditional healers in Guinea provide frontline care for PWE in Guinea with considerable delays in AED initiation, even among a cohort of PWE actively seeking medical care. Engaging with these healers is critical for both influencing community perceptions and appropriately managing epilepsy throughout the country.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
CONCLUSIONS: Traditional healers in Guinea provide frontline care for PWE in Guinea with considerable delays in AED initiation, even among a cohort of PWE actively seeking medical care. Engaging with these healers is critical for both influencing community perceptions and appropriately managing epilepsy throughout the country. PMID: 30731293 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
The accurate segmentation of the brain surface in post-surgical computed tomography (CT) images is critical for image-guided neurosurgical procedures in epilepsy patients. Following surgical implantation of intracranial electrodes, surgeons require accurate registration of the post-implantation CT images to the pre-implantation functional and structural magnetic resonance imaging to guide surgical resection of epileptic tissue. One way to perform the registration is via surface matching. The key challenge in this setup is the CT segmentation, where the extraction of the cortical surface is difficult due to the missing part...
Source: IEE Transactions on Medical Imaging - Category: Biomedical Engineering Source Type: research
ConclusionRobot-guided sEEG electrode implantation using CT-frame referencing and CT-laser-based referencing is most accurate and can serve for high precision placement of electrodes. In contrast, 3.0-T MRI-laser-based referencing is less accurate, but saves radiation. Most trajectories can be reached if alternative routes over less vascularized brain areas are used.This article is part of the Special Issue "Individualized Epilepsy Management: Medicines, Surgery and Beyond".
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
CONCLUSION: Robot-guided sEEG electrode implantation using CT-frame referencing and CT-laser-based referencing is most accurate and can serve for high precision placement of electrodes. In contrast, 3.0-T MRI-laser-based referencing is less accurate, but saves radiation. Most trajectories can be reached if alternative routes over less vascularized brain areas are used. This article is part of the Special Issue "Individualized Epilepsy Management: Medicines, Surgery and Beyond". PMID: 30497893 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
Publication date: December 2018Source: Epilepsy &Behavior, Volume 89Author(s): Niels Hansen, Guido Widman, Svenja Stuff, Albert J. Becker, Juri-Alexander Witt, Hojjat Ahmadzadehfar, Christoph Helmstaedter, Christian E. ElgerAbstractObjectiveParaneoplastic limbic encephalitis (LE) occurs frequently with considerable variability according to literature reports. We thus determined the cancer frequency in mixed LE subtypes sharing the diagnosis of temporal lobe epilepsy (TLE).MethodsAll patients underwent magnetic resonance imaging (MRI) of the brain, electroencephalography (EEG) recordings, neuropsychological testing, imm...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Abstract OBJECTIVE: Paraneoplastic limbic encephalitis (LE) occurs frequently with considerable variability according to literature reports. We thus determined the cancer frequency in mixed LE subtypes sharing the diagnosis of temporal lobe epilepsy (TLE). METHODS: All patients underwent magnetic resonance imaging (MRI) of the brain, electroencephalography (EEG) recordings, neuropsychological testing, immunohistochemistry, and clinical examination together with whole body 2-fluor-2-desoxy-d-glucose (FDG)-positron emission tomography (PET)/computed tomography (CT) to detect cancer in this observatory study. ...
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
Publication date: November 2018Source: Journal of Comparative Pathology, Volume 165Author(s): C. Ros, F. Fernández-Flores, C. de la Fuente, D. Pi, S. Añor, M. Planellas, M. PumarolaSummaryA 10-year-old entire male French bulldog was presented following clusters of generalized tonic–clonic epileptic seizures. Neurolocalization was consistent with a lesion in the left forebrain. Magnetic resonance imaging of the brain revealed a large, ill-defined, intra-axial, space-occupying lesion at the level of the left temporal and parietal lobes, causing marked compression of the adjacent parenchyma. Computed tomog...
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
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