Long-term Risk of Atrial Fibrillation and Stroke in Patients with Atrial Septal Defect Diagnosed in Childhood

The aim of this study is to evaluate the long-term risk of atrial fibrillation (AF) and stroke in patients with atrial septal defect (ASD) diagnosed before the age of 18 years. Patients diagnosed with ASD between 1963-2011 were identified through national Danish registers, of which 1,111 fulfilled the inclusion criteria. Each patient was matched with 10 controls on age and gender. Risk of AF and stroke was assessed using Cox proportional hazards regression. Cumulative incidences were calculated using Fine and Gray ’s competing risk regression.

Source: The American Journal of Cardiology - October 30, 2016 Category: Cardiology Authors: Zarmiga Karunanithi, Camilla Nyboe, Vibeke Elisabeth Hjortdal Source Type: research