A fatal case of Brazilian spotted fever in a non-endemic area in Brazil: the importance of having health professionals who understand the disease and its areas of transmission

This article reports the first fatal case of BSF in Southern Brazil. This case high lights the importance of BSF to be considered as a differential diagnosis for acute hemorrhagic fever in areas where cases of BSF may not be expected.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research

Related Links:

Conclusion: PET/CT added no significant additional benefit over Chest CT in patients with suspected OS or IOTB. PMID: 31743044 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
Publication date: November 2019Source: Mammalian Biology, Volume 99Author(s): Sameer B. Bajaru, Amol R. Kulavmode, Ranjit ManakadanAbstractHuman-dominated ecosystems are characterized by three main processes, viz., habitat degradation, habitat loss and habitat fragmentation, these posing a great threat to biodiversity. However, the relationships between these processes are not clearly understood. Moreover, habitat loss and habitat fragmentation occur at landscape-scale and their effects depend on the spatial scale. We trapped small mammals in a human-dominated area in the northern Western Ghats, India, at 23 sites in three...
Source: Mammalian Biology - Category: Biology Source Type: research
Löchelt The retroviral subfamily of Spumaretrovirinae consists of five genera of foamy (spuma) viruses (FVs) that are endemic in some mammalian hosts [1]. Closely related species may be susceptible to the same or highly related FVs. FVs are not known to induce overt disease and thus do not pose medical problems to humans and livestock or companion animals. A robust lab animal model is not available or is a lab animal a natural host of a FV. Due to this, research is limited and often focused on the simian FVs with their well-established zoonotic potential. The authors of this review and their groups have conducted...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Publication date: 19 November 2019Source: Cell Reports, Volume 29, Issue 8Author(s): Wiebke Hartmann, Marie-Luise Brunn, Nadine Stetter, Nicola Gagliani, Franziska Muscate, Stephanie Stanelle-Bertram, Gülsah Gabriel, Minka BreloerSummaryHelminth parasites infect more than a quarter of the human population and inflict significant changes to the immunological status of their hosts. Here, we analyze the impact of helminth infections on the efficacy of vaccinations using Litomosoides sigmodontis-infected mice. Concurrent helminth infection reduces the quantity and quality of antibody responses to vaccination against seaso...
Source: Cell Reports - Category: Cytology Source Type: research
This study's objective was to estimate the impact of climate, soil, elevation and land cover on the Coccidioides species’ ecological niche. This research used maximum entropy ecological niche modeling based on disease case data from 2015 to 2016. Results found mean temperature of the driest quarter, and barren, shrub, and cultivated land covers influential in characterizing the niche. In addition to hotspots in central California and Arizona, the Columbia Plateau ecoregion of Washington and Oregon showed more favorable conditions for fungus presence than surrounding areas. The identification of influential spatial dr...
Source: Spatial and Spatio-temporal Epidemiology - Category: Epidemiology Source Type: research
Polio cases around have declined globally by more than 99 percent since 1988, but the type 1 poliovirus remains endemic in Pakistan and Afghanistan, where it has made a comeback this year and infected 102 people. Credit: Ashfaq Yusufzai/IPS By James ReinlUNITED NATIONS, Nov 20 2019 (IPS) Efforts to wipe polio off the face of the planet took a step forward this week, with a multibillion-dollar fundraiser in the Middle East helping eradication schemes tackle a virus that disproportionately kills and cripples children in poor countries. Donor governments and philanthropists pledged $2.6 billion on Tuesday in Abu Dhabi to...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Aid Asia-Pacific Development & Aid Featured Global Headlines Health IPS UN: Inside the Glasshouse Poverty & SDGs Regional Categories TerraViva United Nations polio eradication World Health Organization (WHO) Source Type: news
Clinical manifestation of malaria is mainly due to intra-erythrocytic development of Plasmodium parasites. Plasmodium falciparum merozoites, the invasive form of the blood-stage parasite, invade human erythrocytes in a complex but rapid process. This multi-step progression involves interactions between parasite and human host proteins. Here we show that antibodies against a vaccine antigen, PfGAMA, co-immunoprecipitate with PfMSP10. This interaction was validated as direct by surface plasmon resonance analysis. We then demonstrate that antibodies against PfMSP10 have growth inhibitory activity against cultured parasites, w...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Recently, several reports in the Journal of Infection have highlighted the problem of African swine fever (ASF).1,2 ASF is a highly contagious hemorrhagic disease of domestic pigs with a high morbidity and mortality. However, there are currently no effective vaccines to prevent and control this disease. The causative agent of ASF is ASF virus (ASFV), which was described and isolated for the first time in Kenya in 1921.3 ASFV is endemic in most countries in sub-Saharan Africa and Sardinia. After 1957, this virus spread into European and American countries, and recently, it spread to Asia.
Source: Journal of Infection - Category: Infectious Diseases Authors: Source Type: research
Conclusions: Because serum serology can be negative at presentation, lumbar puncture is a valuable tool when diagnosing LB among children with facial palsy. Pleocytosis and increased protein and CXCL13 values in the CSF suggest LB as the cause of facial palsy.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
ConclusionsOur results define immune responses to O-specific polysaccharide in immunologically naive humans with cholera, find that they are largely IgM and IgA, may be blunted in blood group O individuals, and differ in a number of significant ways from responses in previously humans. These differences may explain in part varying degrees of protective efficacy afforded by cholera vaccination between these two populations. Trial registration numberClinicalTrials.gov NCT01895855.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
More News: Brazil Health | Endemics | International Medicine & Public Health | Tropical Medicine