Targeting miR-29 induces apoptosis of osteosarcoma MG-63 cells via regulation of TGF- β1/PUMA signal.

CONCLUSIONS: Targeting miR-29 exhibits significant in vivo and in vitro anti-tumor activities in OS through a novel mechanism resulting in inhibition of TGF-β1 expression and inducing PUMA expression. PMID: 27649654 [PubMed - as supplied by publisher]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research