Mas receptor contributes to pregnancy-induced cardiace remodeling

In conclusion, these data show that while Mas receptor blockade or deletion decreases physiological hypertrophy of pregnancy, it is associated with more extracellular matrix deposition. These alterations are associated with improvement of the cardiac function through Mas-independent mechanism.

Source: Clinical Science - September 12, 2016 Category: Biomedical Science Authors: Carmos-Silva, C., Almeida, J., Macedo, L., Melo, M. B., Pedrino, G., Santos, F., Biancardi, M., Santos, R. A. S., Carvalho, A., Mendes, E., Colugnati, D., Mazaro-Costa, R., Castro, C. Tags: PublishAheadOfPrint Source Type: research