High Sensitivity C-Reactive Protein and Risk of Stroke in Atrial Fibrillation (From the Reasons for Geographic and Racial Differences in Stroke Study [REGARDS])

The relationship between inflammation and prothrombotic state in atrial fibrillation (AF) is well recognized. This suggests a potential role for high sensitivity C-reactive protein (hs-CRP), a marker of systemic inflammation, in improving prediction of stroke in participants with AF. Cox proportional hazard analysis was used to examine the risk of stroke in 25,841 participants (40% black, 55% women) with and without AF who were enrolled in the REGARDS study between 2003 and 2007. Baseline AF (n=2,132) was ascertained by electrocardiogram and self-reported history of previous physician diagnosis.

Source: The American Journal of Cardiology - September 13, 2016 Category: Cardiology Authors: Farah Z. Dawood, Suzanne Judd, Virginia J. Howard, Nita A. Limdi, James F. Meschia, Mary Cushman, George Howard, David M. Herrington, Elsayed Z. Soliman Source Type: research