Artefactual origin of biphasic cortical spike-LFP correlation

AbstractElectrophysiological data acquisition systems introduce various distortions into the signals they record. While such distortions were discussed previously, their effects are often not appreciated. Here I show that the biphasic shape of cortical spike-triggered LFP average (stLFP), reported in multiple studies, is likely an artefact introduced by high-pass filter of the neural data acquisition system when the actual stLFP has a single trough around the zero lag.
Source: Journal of Computational Neuroscience - Category: Neuroscience Source Type: research