Dermoscopy in General Dermatology: A Practical Overview

AbstractOver the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. dermatoses presenting with erythematous-desquamative patches/plaques (plaque psoriasis, eczematous dermatitis, pityriasis rosea, mycosis fungoides and subacute cutaneous lupus erythematosus), papulosquamous/papulokeratotic dermatoses (lichen planus, pityriasis rosea, papulosquamous sarcoidosis, guttate psoriasis, pityriasis lichenoides chronica, classical pityriasis rubra pilaris, porokeratosis, lymphomatoid papulosis, papulosquamous chronic GVHD, parakeratosis variegata, Grover disease, Darier disease and BRAF-inhibitor-induced acantholytic dyskeratosis), facial inflammatory skin diseases (rosacea, seborrheic dermatitis, discoid lupus erythematosus, sarcoidosis, cutaneous leishmaniasis, lupus vulgaris, granuloma faciale and demodicidosis), acquired keratodermas (chronic hand eczema, palmar psoriasis, keratoderma due to mycosis fungoides, keratoderma resulting from pityriasis rubra pilaris, tinea manuum, palmar lichen planus and aquagenic palmar keratoderma), sclero-atrophic dermatoses (necrobiosis lipoidica, morphea and cutaneous lichen sclerosus),...
Source: Dermatology and Therapy - Category: Dermatology Source Type: research

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Conditions:   Allergy;   Asthma;   Food Allergy;   Allergic Sensitisation;   Atopic Dermatitis Intervention:   Sponsors:   Pontificia Universidad Catolica de Chile;   University of Chile;   Comisión Nacional de Investigación Científica y Tecnológica Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Autoimmune Disorder;   Rheumatoid Arthritis;   Systemic Lupus Erythematosus;   Primary Sjögren's Syndrome Interventions:   Drug: branebrutinib;   Drug: abatacept;   Drug: branebrutinib placebo Sponsor:   Bristol-Myers Squibb Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Ishizaki S, Watanabe S, Sawada M, Ninomiya J, Otani T, Tanaka M, Harada T, Kamei K Abstract An otherwise healthy 3-year-old girl presented with a several-month history of scaly lesions on her palms and soles. The lesions on the palms and right sole had been successfully treated with a steroid for pompholyx by a nearby dermatology clinic, but the lesion on the left sole persisted and spread to the back of the foot. On the initial visit, the patient exhibited an itchy and scaly erythematous left foot lesion. Direct microscopic examination of the scales revealed a considerable amount of fungal elements. A dia...
Source: Medical Mycology Journal - Category: Biology Tags: Med Mycol J Source Type: research
ECZEMA tends to be more common in children and often develops before their first birthday. But for one baby, eczema took over when she was just six months old, and it was so bad she couldn ’t sleep.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Abstract Itching, or pruritus, can be defined as an unpleasant sensation that evokes the desire to scratch. Pruritus is most commonly associated with a primary skin disorder such as atopic dermatitis (AD), psoriasis, etc., and can have a major impact on the quality of life of those patients. Itch-induced scratching can further damage the skin barrier, leading to a worsening of symptoms. For that reason, it is important to manage pruritus. Topical glucocorticoids are commonly the first-line therapy in the management of AD and psoriasis patients. We found that topical glucocorticoids induce pruritus in mice under ce...
Source: Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan - Category: Drugs & Pharmacology Authors: Tags: Yakugaku Zasshi Source Type: research
It was on November 21st that I was last in Copenhagen, not to have some of that famous Æbleflæsk but to moderate an OECD event. I was tasked to challenge health ministers and other policy makers about the impact of advanced technologies on patients’ lives and what regulations would facilitate these changes. It was encouraging to see country leaders take a positive stance towards digital health and to hear about concrete examples as to how they are implementing technology to modify their local healthcare landscape. This experience served as an inspiration to write this article. In it we will highli...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Healthcare Policy digital health Medicine technology healthcare design Source Type: blogs
Authors: Saenza De San Pedro A, Lopes MP, Sokolova A, Abreu C, Lopes C Abstract Summary: Atopic Dermatitis (AD) affects both children and adults and is a serious health concern in many countries. AD is a complex disease with host and environmental factors underlying its pathology. Its treatment is multidimensional reflecting the diverse nature of its triggers and includes emollients, topical steroids and calcineurin inhibitors among others. Immunological dysfunction can be addressed broadly with systemic immunosupressors and specifically with monoclonal antibodies. Dupilumab, which targets IL-4 and IL-13 was grante...
Source: European Annals of Allergy and Clinical Immunology - Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research
DISCUSSION: Since 2014, the worldwide "epidemic" of sensitization to MI has been subsiding in Central Europe, thanks to corresponding restrictions on use. Since 2008, there is no longer any widespread exposure to MDBGN; the new, higher test concentration elicits many false-positive test reactions and explains the sudden rise in positive patch test reactions since 2016. Despite widespread use, phenoxyethanol, benzoates, benzyl alcohol, parabens and sorbates rarely cause allergic reactions. Therefore, they can be recommended for cosmetics from the epidemiological-allergological point of view. PMID: 31792581 [Pu...
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
We report on a patient with severe psoriasis vulgaris who developed drug-induced interstitial lung disease (DILD) during treatment with ustekinumab. The diagnosis was based on coincidence with start of therapy, high-resolution computer tomography of the thorax and bronchoalveolar lavage. After discontinuation of the treatment with ustekinumab the clinical symptoms and the chest scan results improved. This case highlights a possible adverse event of ustekinumab. PMID: 31792580 [PubMed - as supplied by publisher]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
Publication date: Available online 28 November 2019Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Sonia S. Pandey, Furqan A. Maulvi, Priya S. Patel, Manish R. Shukla, Kinjal M. Shah, Arti R. Gupta, Shrikant V. Joshi, Dinesh O. ShahAbstractPsoriasis is a widespread chronic disease affecting 1-3% of total population. In major cases (>80%), it is treated by topical application of corticosteroids. However, the topical route is very challenging due to physico-chemical nature of diseased stratum corneum and so no single treatment works for every patient. The oral route showed severe side effects due to systemic immu...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
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