A Green One-pot Synthesis of 4-hydroxychromenylarylmethyl-6-hydroxypyrimidine-2,4-diones Using Titanium Dioxide Nanowires as an Effective and Recyclable Catalyst.

A Green One-pot Synthesis of 4-hydroxychromenylarylmethyl-6-hydroxypyrimidine-2,4-diones Using Titanium Dioxide Nanowires as an Effective and Recyclable Catalyst. Comb Chem High Throughput Screen. 2016 Sep 7; Authors: Eskandari K, Karami B Abstract Catalytic reaction between barbituric acid (or N,N-dimethyl barbituric acid), 4-hydroxycoumarin, and a wide range of aryl aldehydes by employing titanium dioxide nanowires (TiO2 NWs) is described which led efficiently to obtain 12 newly prepared products successfully. Starting materials in the presence of catalytic amounts of TiO2 NWs as a key factor were condensed together via three C-C bond formation to obtain target products. This procedure profits some advantages such as an efficient, environmental safety and high recyclability of nano-catalyst. PMID: 27604955 [PubMed - as supplied by publisher]
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Tags: Comb Chem High Throughput Screen Source Type: research