Reoptimization of intensity-modulated proton therapy plans based on linear energy transfer
We present a treatment planning method for intensity-modulated proton therapy based on prioritized optimization, which avoids elevated LET in critical organs. The approach is demonstrated for meningiomas, base-of-skull chordomas and ependymomas where the brainstem, chiasm or optic nerve overlay the target volume.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Jan Unkelbach, Pablo Botas, Drosoula Giantsoudi, Bram Gorissen, Harald Paganetti Source Type: research
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