Chronic corticosterone administration reduces dendritic complexity in mature, but  not young granule cells in the rat dentate gyrus.

CONCLUSION: These data suggest that mature neurons are likely more vulnerable to chronic exposure to CORT; this may be due to their higher expression of GRs when compared to younger DG neurons.
PMID: 27567758 [PubMed - as supplied by publisher]

Source: Restorative Neurology and Neuroscience - August 30, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research