Multiple Meningiomas in a Patient with Cowden Syndrome

Conclusions The development of multiple meningiomas in a patient with predisposition for tumor is more than coincidental. Though PTEN mutations and deletions have not been shown to be critical for meningioma development, this case challenges that conclusion. In light of recent genetic advances in meningioma molecular pathogenesis, the role of the PTEN/AKT/PI3K pathway is discussed. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text

Source: Journal of Neurological Surgery Reports - August 23, 2016 Category: Neurosurgery Authors: Pain, Margaret Darbinyan, Armine Fowkes, Mary Shrivastava, Raj Tags: Case Report Source Type: research