C-Terminal to Intact Fibroblast Growth Factor 23 Ratio in Relation to Estimated Glomerular Filtration Rate in Elderly Population

Conclusions:Our results suggest impairment in the cleavage of the C-terminal FGF23 fragments with the deterioration of kidney excretory function and age in the elderly population. Inflammation and low serum iron level seems to diminish degradation capacity of FGF23 fragments.Kidney Blood Press Res 2016;41:519-526
Source: Kidney and Blood Pressure Research - Category: Urology & Nephrology Source Type: research