Subacute Toxicity Profile of the Leaves of Colocasia esculenta L. Schott in Albino Rats
This study reports the sub-acute toxicity effects of C. esculenta (CE) crude aqueous leaves extracts in albino rats. Methodology: Daily doses of 400 and 800 mg kg1 b.wt. of crude aqueous extracts of the fresh and dried leaves of CE were administered orally to different sets of rats for 28 days. Body weights, Relative Organ Weights (ROW), haematological analysis, serum biochemical assay and histopathological changes of vital organs were used to evaluate the toxic effects of the extracts after treatments. Results: Results revealed that treatment with CE causes adverse effects on body weight. The tested doses did not provoke significant changes in haematological and biochemical parameters of rats except an increase in alkaline phosphatase of treated rats (p
Alzheimer ’s is the number one mental disorder diagnosed in the elderly with over 5.4 million people afflicted in 2016. According to Maplewood's records 43% of patients have dementia, 45% have depression and 21% have both. These two diagnoses have symptoms of sleep disturbances, agitated behavior and sadnes s which can increase the risk for falls. Often medications given to treat depression can lead to somnolence, decreased appetite, constipation, confusion or possible arrhythmia. Circadian rhythms are controlled in the suprachiasmatic nucleus (SCN) located in the hypothalamus by a monosynaptic pathway with the retin...
ConclusionsGI symptoms are highly prevalent in people on dialysis; however, the evidence base is limited and further investigation of preventable causes and potential interventions such as medications and diet is required in future research.
ConclusionsThe increased research data and growing consumer awareness of the health benefits of kiwifruit provide logical motivation for their regular consumption as part of a balanced diet. Kiwifruit should be considered as part of a natural and effective dietary strategy to tackle some of the major health and wellness concerns around the world.
An 85-year-old frail female presented for ileocolonoscopy under conscious sedation for workup of symptomatic constipation. Digital rectal examination (DRE) before scope insertion revealed a palpable ring structure with a smooth surface. In accordance, endoscopic visualization of the rectum revealed with an excavating doughnut-shaped impression at the anterior rectal wall with normal overlying mucosa. (Figure 1) While ileocolonoscopy proved otherwise normal, dedicated medical history and additional imaging studies confirmed the presence of a partly dislodged intravaginal pessary.
This study shows that andrographolide inhibits the development of osteoclasts ( = the cells that chew away at our bones, which is fine in a healthy situation, not fine in cancer where everything goes nutso), while increasing the presence of osteoblasts (bone builders). The researchers say that the current therapies used to treat osteolytic diseases have many unwanted side effects. And they’re not just referring to bisphosphonates (which can cause osteonecrosis of the jaw) but also to new treatments such as the monoclonal antibody denosumab, Denosumab can cause low calcium levels, weakness, constipation, bac...
ConclusionPatients who have undergone prostate biopsy and treatment decision-making for Pca experience a decline in HRQoL. Choosing treatment with a curative intent was associated with greater decline in HRQoL. Interventions aimed at optimism and decision self-efficacy could be helpful to reduce HRQoL impairment around the time of prostate biopsy and treatment decision-making.
This study aimed to determine the knowledge, attitudes, and practices of Turkish oncology nurses regarding CAM. A descriptive cross-sectional survey of 127 participants was conducted in Ankara, Turkey. A semistructured questionnaire including characteristics, knowledge, attitudes, and practices of oncology nurses toward CAM was administered to participants. We found that more than half of nurses (54.0%) surveyed had no information on CAM modalities. Most oncology nurses (81.1%) used audiovisual media sources to obtain CAM information. Many nurses (81.3%) reported not using any CAM in cancer care, and only 26.8% recommended...
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