Assessment of pharyngeal airway volume in adolescent patients affected by bilateral cleft lip and palate using cone beam computed tomography.

Assessment of pharyngeal airway volume in adolescent patients affected by bilateral cleft lip and palate using cone beam computed tomography. Angle Orthod. 2014 Mar 25; Authors: Celikoglu M, Ucar FI, Sekerci AE, Buyuk SK, Ersoz M, Sisman Y Abstract Abstract Objective: To test the null hypothesis that there were no significant differences for pharyngeal airway volumes between the adolescent patients affected by bilateral cleft lip and palate (BCLP) and well-matched controls using cone beam computed tomography. Materials and Methods: The study sample consisted of 16 patients (11 female and 5 male; mean [SD] age 14.1 [2.1] years) affected by BCLP and 16 patients (10 female and 6 male; mean [SD] age 13.4 [2.0] years) as age- and sex-matched control group. Craniofacial measurements and pharyngeal airway dimension, area, and volume measurements of patients in both groups were calculated and statistically examined using Student's t-test and multiple linear regression analyses. Results: Statistically significant differences were found between the BCLP and control groups for SNB (P
Source: The Angle Orthodontist - Category: Dentistry Authors: Tags: Angle Orthod Source Type: research

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Publication date: Available online 22 February 2020Source: Oral and Maxillofacial Surgery Clinics of North AmericaAuthor(s): Veerasathpurush Allareddy, Richard Bruun, James MacLaine, Michael R. Markiewicz, Ramon Ruiz, Mark A. Miller
Source: Oral and Maxillofacial Surgery Clinics of North America - Category: ENT & OMF Source Type: research
Publication date: Available online 19 February 2020Source: Journal of Evidence Based Dental PracticeAuthor(s): Lubomyr Ravlyk, Sukaynah Alawami, Thikriat Al-Jewair
Source: Journal of Evidence Based Dental Practice - Category: Dentistry Source Type: research
CONCLUSIONS &IMPLICATIONS: Whilst a medical model and linguistic approaches are often central in assessments of age-3 cleft speech, this review highlights the importance of developmental and functional approaches to assessment. Cross-linguistic single-word assessments show potential, and would facilitate the comparison of UK speech outcomes with other countries. Further research should explore the impact of different speech samples and rating scales on assessment validity and listener reliability. PMID: 32077212 [PubMed - as supplied by publisher]
Source: International Journal of Language and Communication Disorders - Category: Speech-Language Pathology Authors: Tags: Int J Lang Commun Disord Source Type: research
CONCLUSIONS: Palate re-repair achieves normal speech resonance in many but not all patients with VPI. Further research is needed to identify the specific examination and imaging findings that predict successful correction of VPI with re-repair. PMID: 32070129 [PubMed - as supplied by publisher]
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
Abstract OBJECTIVE: To detect the appearance and distribution of factors regulating remodeling, innervation, growth, and vascularity of the nasal tissue affected by cleft lip and palate (CLP). DESIGN: Morphological analysis of human tissue. SETTING: Cleft and craniofacial center. PARTICIPANTS: Fifteen patients who underwent CLP rhinoplasty, 7 control patients. INTERVENTIONS: Rhinoplasty. MAIN OUTCOME MEASURES: Immunohistochemistry was performed with protein gene product (PGP) 9.5, transforming growth factor β1 (TGFβ1), vascular endothelial growth factor (VEGF), cluster of differe...
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
CONCLUSIONS: These new genetic variants will add to the spectrum of known OFD1 mutations associated with the OFD1 disorder. Our study also confirms the variable phenotypic presentation of OFD1 and its well-recognized association with central nervous system malformations and renal anomalies. Molecular diagnostic confirmation achieved in these families will have positive implications for their medical management. PMID: 32064904 [PubMed - as supplied by publisher]
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
ConclusionsUnsurprisingly, both the inpatient and outpatient burdens of care are influenced by the complexity of the cleft and increase with worsening severity. Our results will help inform parents of the likely trajectory their child will face when diagnosed with each subtype of cleft. The 2014 data shows that modern cleft care is changing; a combination of reduced hospital stay and the addition of streamlined outpatient appointments will both be of great benefit. The influence of modern day life will hopefully reduce the associated burden that has been highlighted in this paper and it is vital the benefits of modernisati...
Source: European Journal of Plastic Surgery - Category: Cosmetic Surgery Source Type: research
Publication date: Available online 12 February 2020Source: Meta GeneAuthor(s): Ginila T. Raju, Bhaskar V.K.S. Lakkakula, Jyotsna Murthy, Solomon F.D. PaulAbstractPlatelet derived growth factor -c (PDGF-C) plays a major role in embryogenesis especially during the neural crest cell induction. Animal studies revealed that PDGF signalling is required for orofacial development. Further, Pdgfc knockout mice also showed cleft face phenotype. The present study aims to evaluate the parental transmission effect of PDGF-C gene variants in the etiology of non-syndromic cleft lip with or without cleft palate (NSCL/P) in South Indian po...
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
Abstract OBJECTIVE: To translate and validate the velopharyngeal insufficiency (VPI) effects on life outcomes (VELO) instrument into Nepali, and test its internal consistency and validity. DESIGN: Quality-of-life instrument translation and validation. SETTING: Community served by Nepal's craniofacial referral hospital. PARTICIPANTS: Twenty-three postpalatoplasty children with VPI, 19 family guardians of VPI cases, and 29 non-VPI controls. INTERVENTIONS: The VELO instrument was translated to Nepali by 2 independent bilingual translators, reconciled, backward-translated, compared, and modified us...
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
Abstract OBJECTIVE: To test for systematic age changes in cleft children based on dental age. DESIGN: Retrospective case-control longitudinal study. SETTING: One orthodontic solo practice. PATIENTS: Nonsyndromic, complete cleft lip and palateCLP cases, either unilateral or bilateral (102 children; 370 radiographs), between 4 and 16 years of age. INTERVENTIONS: Children were treated with a team approach, but only orthodontic radiographs were studied. MAIN OUTCOME MEASURE: The principal outcome measure was dental age of the cleft cases compared to a sex-specific sample of phenotypically norm...
Source: The Cleft Palate-Craniofacial Journal - Category: ENT & OMF Authors: Tags: Cleft Palate Craniofac J Source Type: research
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