NIH-funded study supports surgery as treatment for myasthenia gravis

In a global study of myasthenia gravis, an autoimmune disease that causes muscle weakness and fatigue, researchers found that surgical removal of an organ called the thymus reduced patients ’ weakness, and their need for immunosuppressive drugs. The study, published in the New England Journal of Medicine, was partially funded by the National Institutes of Health.
Source: NINDS Press Releases and News: National Institute of Neurological Disorders and Stroke - Category: Neurology Source Type: news

Related Links:

, Fortuna A Abstract Direct oral anticoagulants (DOACs) are first-line drugs used for the treatment of venous thromboembolism and prevention of stroke in patients with atrial fibrillation. These drugs do not require the regular biochemical monitoring that is mandatory for warfarin, and they exhibit shorter half-lives and have a faster onset of action. Since recent real-world studies evidence a higher prevalence of adverse side effects than what was anticipated in clinical trials, monitoring the plasma concentrations of DOACs is being used to personalize their pharmacotherapy, in accordance to the characteristics o...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
Conclusions: Patients with low income, family caregiver, and no insurance have a poorer prognosis after ischemic stroke that can be partly explained by intermediate variable in the patients' demographic characteristics, cardiovascular disease, behavior lifestyle, and stroke severity. Abbreviations: DALYs: disability-adjusted life years; SES: socioeconomic status; FMC: free medical care; MIUR: medical insurance for urban residents; MIUE: medical insurance for urban employees; NCMS: new rural cooperative medical scheme ; NIHSS: National Institute of Health Stroke Scale ; mRS: modified Rankin scale; OR: odds ratios; CI: confi...
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Hello, I am new here- so I will give some background. I recently graduated with my bachelors in Communication Sciences and Disorders. I was sure throughout my undergrad experience that I wanted to be a medical SLP. I loved learning neurology, anatomy, dysphagia/TBI/stroke, etc. Then, in my last semester my mother unfortunately passed away and due to that experience- I have developed a big interest in going into psychiatric medicine. This has led me to strongly consider becoming a PMHNP. I... PMHNP- One concern
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Clinicians [ RN / NP / PA ] Source Type: forums
ConclusionsIn summary, our data suggest that microbial antigens may affect NMOSD outcomes by favoring an imbalance between Th17 and TFH-like cells and regulatory T cell subsets.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 17 June 2019Source: Brain, Behavior, and ImmunityAuthor(s): Roman Fischer, Tanja Padutsch, Valerie Bracchi-Ricard, Kayla L. Murphy, George.F. Martinez, Niky Delguercio, Nicholas Elmer, Maksim Sendetski, Ricarda Diem, Ulrich L.M. Eisel, Richard J. Smeyne, Roland E. Kontermann, Klaus Pfizenmaier, John R. BetheaAbstractTumor necrosis factor receptor 2 (TNFR2) is a transmembrane receptor that promotes immune modulation and tissue regeneration and is recognized as a potential therapeutic target for multiple sclerosis (MS). However, TNFR2 also contributes to T effector cell function and macroph...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
A prospective cohort study of nearly 8000 people who were followed for 8 years identified components of the immune system that either increase or decrease stroke risk.Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Conclusions:GCA is the most prevalent systemic vasculitis in the elderly. It can present with a wide variety of symptoms ranging from fatigue, headache, visual loss, and even stroke. However as noted in this case, isolated CN-VI palsy can be a very rare, early manifestation of GCA. As GCA responds well to corticosteroid therapy, prompt diagnosis and treatment is critical to prevent and/or limit neurologic sequelae. As highlighted by this case, in the event of recurrent incidents and absence of other diagnosis; GCA should be considered even if headache is absent.Disclosure: Dr. Lunagariya has nothing to disclose. Dr. Patel ...
Source: Neurology - Category: Neurology Authors: Tags: CNS Inflammatory Diseases and Differential Diagnosis II Source Type: research
French Intensive Care Society, International congress - Réanimation 2016. Ann Intensive Care. 2016 Jun;6(Suppl 1):50 Authors: Jaillette E, Girault C, Brunin G, Zerimech F, Chiche A, Broucqsault-Dedrie C, Fayolle C, Minacori F, Alves I, Barrailler S, Robriquet L, Delaporte E, Thellier D, Delcourte C, Duhamel A, Nseir S, Valette X, Desmeulles I, Savary B, Masson R, Seguin A, Daubin C, Sauneuf B, Verrier P, Pottier V, Orabona M, Samba D, Viquesnel G, Lermuzeaux M, Hazera P, Hanouz JL, Parienti JJ, Du Cheyron D, Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas ...
Source: Australian Family Physician - Category: Primary Care Authors: Tags: Ann Intensive Care Source Type: research
More News: Autoimmune Disease | Health | Myasthenia Gravis | National Institutes of Health (NIH) | Neurology | Neurosurgery | Stroke | Study