Resistin-like molecule- α causes lung injury in rats with acute pancreatitis by activating the PI-3K/Akt-NF-κB pathway and promoting inflammatory cytokine release.

CONCLUSIONS: RELMα is associated with lung injury severity in SAP. RELMα augments inflammatory activity by increasing inflammatory cytokine release.
PMID: 27492801 [PubMed - as supplied by publisher]

Source: Current Molecular Medicine - August 1, 2016 Category: Molecular Biology Authors: Wang WY, Chen Y, Su X, Tang D, Ben QW, Yao WY, Chen P, Yuan YZ Tags: Curr Mol Med Source Type: research