Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice

Obesity is associated with vascular inflammation, fibrosis and reduced high-density lipoproteins (HDL)-cholesterol. We aimed to investigate whether adenoviral gene transfer with human apolipoprotein (apo) A-I (Ad...

Source: Journal of Inflammation - August 2, 2016 Category: Allergy & Immunology Authors: Frank Spillmann, Bart De Geest, Ilayaraja Muthuramu, Ruhul Amin, Kapka Miteva, Burkert Pieske, Carsten Tsch öpe and Sophie Van Linthout Source Type: research