IL-33 Drives Augmented Responses to Ozone in Obese Mice

Conclusions: Our data indicate that IL-33 contributes to augmented responses to ozone in obese mice. Obesity and ozone also interacted to promote type 2 cytokine production in γδ T cells and ILC2 in the lungs, which may contribute to the observed effects of IL-33.

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Citation: Mathews J, Krishnamoorthy N, Kasahara DI, Cho Y, Wurmbrand AP, Ribeiro L, Smith D, Umetsu D, Levy BD, Shore SA. IL-33 Drives Augmented Responses to Ozone in Obese Mice. Environ Health Perspect; http://dx.doi.org/10.1289/EHP272
Received: 31 October 2015
Revised: 23 February 2016
Accepted: 7 June 2016
Published: 29 July 2016
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Source: EHP Research - July 29, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research