Hypertension: Role of p66Shc in renal vascular dysfunction

Nature Reviews Nephrology 12, 442 (2016). doi:10.1038/nrneph.2016.89 Author: Ellen F. Carney A new study provides insights into the mechanisms by which regulation of renal microvascular tone is impaired in salt-sensitive hypertension- induced nephropathy. Andrey Sorokin and colleagues report that overexpression of the SH2 adaptor protein p66Shc promotes renal vascular dysfunction in this disease.p66Shc is known
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research